Found 152 matching trials
MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
PHASE1This phase I/II trial studies the side effects of panobinostat nanoparticle...
Location
University of California, San Francisco
Oral LBH589 in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL)
PHASE2The purpose of the study is to find out the effects and the safety of an in...
Location
H. Lee Moffitt Cancer Center and Research Institute
Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase
PHASE2This study will evaluate the efficacy and safety of LBH589B in adult patien...
Location
Novartis Investigative Site
Safety Study of LBH589 When Given in Combination With Bortezomib in Adult Patients With Multiple Myeloma
PHASE1This study comprises of a dose-escalation and dose expansion phase and will...
Location
Innovative Medical Research of South Florida Dept.ofInnovativeMedResearch
Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase
PHASE2This study will evaluate the efficacy and safety of LBH589B in adult patien...
Location
City of Hope National Medical Center
Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosis
PHASE1This study will assess safety as well as establish a Recommended Phase II d...
Location
Novartis Investigative Site
Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia
PHASE1RATIONALE: Panobinostat and imatinib mesylate may stop the growth of cancer...
Location
City of Hope Medical Center
A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
PHASE1The purpose of this study was to combine the PDR001 checkpoint inhibitor wi...
Location
UCLA Santa Monica Hematology / Oncology SC
Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat
PHASE1The purpose of this study is to treat metastatic melanoma with a combinatio...
Location
University of Iowa Hospitals and Clinics
A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors
PHASE1The primary purpose of this open-label study is to investigate the interact...
Location
Nevada Cancer Institute